Correct Opening of the Nanosynt Ampoule
With Nanosynt, the FGM 100% synthetic bone graft, you achieve unparalleled results in just a few steps, benefiting both the patient and the professional.
See how simple it is:
1
Remove the ampoule from the smart packaging
2
To open the ampoule, simply tilt it at a 45° angle with one hand and press the protective cap with the other until it breaks.
3
Pour the contents into a sterile container and hydrate it with 5 to 8 drops.
4
Handle the material until it reaches the desired consistency
5
Done!
You can now place the material in the desired area
More bone in less time
Nanosynt is a synthetic bone replacement material, based on biphasic calcium phosphate (60% hydroxyapatite and 40% ß-tricalcium phosphate), non-toxic, radiopaque and highly biocompatible. It has an excellent osteoconductive action, being reabsorbed and replaced by living bone tissue during bone remodeling.
Commercial Presentation
- 200 to 500 µm – 4 portions of 0.27 cc
- 200 to 500 µm – 2 portions of 0.27 cc
- 500 to 1000 µm – 4 portions of 0.27 cc
- 500 to 1000 µm – 2 portions of 0.27 cc
- 1000 to 2000 µm – 2 portions of 0.53 cc
Dimensional Stability
The blocks provide stability and maintenance of the framework during the replacement process, which is crucial in larger defects or in áreas Where preservation of the bone contou ris essential.
Ease of Handling
The block is easy to handle and can be sculpted according to the shape of the boné defect., allowing for precise and personalized adaptation.
Reduction of Micromovements
In addition to providing a rigid structure, the blocks can be stabilized with screws, which reduces the risk of micromovements and increases the predictability of results.
Commercial Presentation
- Nanosynt Block 05x10x10mm
- Nanosynt Block 10x10x10mm
- Nanosynt Block 08x20x20mm
Benefits
High porosity (80% to 90%)
It favors vascularization, fixation of osteoblasts and bone deposition. It allows the connection of the bone tissue in formation and / or neoformed with the surrounding bone tissue. It avoids encapsulation of the forming bone tissue by fibrous conjuctive tissue.
Safety
100% synthetic, contributing to better biological safety for eliminating any risk of contamination
Excellent hydration
5 to 8 drops per serving (0.25g) – Hydrate drop by drop.
Osteoconductivity
Its excellent osteoconductive structure, allows for the vascularization and the fast cellular deposition.
Convenience
Available in fractioned form (2 or 4 ampoules of 0.27cc), resulting in minimal material waste.
Excellent handling
For being higly hydrophilic, it must be hydrated “drop by drop” with saline or blood, forming a cohesive mass of excellent usability.
Scientifically Proven
Nanosynt: Histologial and histomorphometric analyses of a new boné substitute. The use of nanotechnology towards a better osteoconductive pattern.
Conclusion
“All biomaterials demonstrated similar behaviors throughout the study in histomorphometric, histological, and biocompatibility analyses. However, the synthetic material Nanosynt showed a higher level of bone formation and defect space maintenance when compared to Competitor 1 and Competitor 2 materials during the two in vivo periods of the present study.”
Percentage of bone, remaining biomaterial, and soft tissue during the evaluated periods.
SOURCE: Freitas G., Tovar N., Ganato R., Marin C., Coelho P.G. NanoSynt: Histological and histomorphometric evaluation of a new bone substitute. The use of nanotechnology in achieving a better standard of osteoconduction. ImplantNews. 2014;11(3):296–301.
Randomized Controlled Double-Blind Clinical Trial for Biological Evaluation of Two Synthetic Bone Substitutes
Newly Formed Bone
Conclusion
“After the completion of this clinical trial, we can conclude that, from a clinical perspective, both experimental materials are easy to handle, offer excellent manipulation for alveolar filling, and are radiopaque enough for follow-up through imaging exams.
Both materials are biocompatible and osteoconductive. They both allowed the placement of implants after 3 and 6 months without complications or implant loss and preserved the alveolar architecture. The Biomaterial Group 1 (Nanosynt), after 6 months, showed a higher amount of newly formed bone compared to the other groups. Both materials proved to be safe and effective for use in humans.”
Histomorphometric evaluation of experimental groups for newly formed bone after 3 and 6 months of implantation (n=5). * = p<0.05 and *** = p<0.001.
